WATCH: Kamala Harris weighs in on school debate in light of mixed messages from the White House

"So our goal is that as many K-8 schools will reopen within the first 100 days ," Harris said in response to a question on how soon schools can be reopened, "Our goal will be that they will be open five days a week."

On Thursday, Psaki said "The President wants schools to open safely and in accordance with science, and we are going to listen to science and medical experts. The CDC guidelines, we expect them to come out tomorrow," she said.

"We are eager to hear more about the clear science-based guidelines for opening schools and how we can do that safely, and how we can keep them open. The president will not rest until every school is open five days a week. That is our goal. That is what we want to achieve."

And she touted the need for the $1.9 trillion American Rescue Plan to get schools open safely.

On Wednesday, Psaki said Biden's "goal that he set is to have the majority of schools, so more than 50 percent, open by day 100 of his presidency. And that means some teaching in classrooms. So at least one a day week, hopefully it's more! And obviously it is as much as is safe in each school and local district."

The reporter asked for clarity, saying "When you say 'some teaching,' you didn't use the same majority qualifier there, you just said 'some teaching' in schools, some teachers in school, not the majority of teachers in school in the majority of classrooms."

"Teaching at least one day a week in the majority of schools by day 100," Psaki said.

At Tuesday night's CNN townhall, Biden said "That's what was reported, that's not true," Biden said. "It was a mistake in the communication. What I'm talking about, I said opening the majority of school in K-8th grade, because they are the easiest to open, the most needed to be open in terms of the impact on children and families having to stay home—"

"So when do you think that would be, K-8, five days a week," Cooper interrupted.

"I think we'll be close to that at the end of the first 100 days. We've had a significant percentage of them being able to be opened. My guess is there's probably going to push to open all summer, like it's a different semester."

Biden took questions from a parent of four, who asked when kids were going to be back in schools. The questioner, Kevin Michael, who was introduced by Anderson Cooper as an independent, had concerns over the now year-long disruption in proper schooling and wanted to know "the plan to get students back into brick and mortar buildings?"

Biden said that kids in grades K-8 should go back to school, but that it's "harder" to get high schools open without a rehaul of school ventilation systems. He also said that there's problems with school busses, and called for teachers "to be moved up in the hierarchy" for vaccines.

Biden referenced the CDC's report that there should be "smaller classes, more ventilation, making sure that everybody has masks and is socially distanced, and you have less, fewer students in one room."

"It's about needing to be able to socially distance, smaller classes, more protection, and I think that teachers and the folks that work in the school, the cafeteria workers, and others, should be on the list of preferred to get a vaccination."

The CDC recommended that teachers do not have to be vaccinated for schools to reopen. Biden has also touted his $1.9 trillion American Rescue Plan, which has some $130 billion earmarked for schools. This money, his administration has said, is necessary for schools to reopen.

Florida schools have been open since August, and Governor Ron De Santis said "And yet, we're 34th our of 50 states and DC for COVID-19 cases on a per capita basis for children. 33 states have more cases per capita than Florida for children, and many of those don't have a lot of in-person instruction in school."

"It does not require another hundred billion dollars," De Santis said. "The school reopening plan that makes the most sense, if you want to open schools, open them. Open the door. Let them come in and learn."