WATCH: Mark McCloskey announces run for Missouri Senate seat

"An angry mob marched to destroy my home and kill my family," he said on his campaign video, "I took a stand to defend them."

He then shifted that message to one that applied to all Americans. "When the mob comes to destroy our home, our state, our nation—I'll defend it," McCloskey stated.

McCloskey filed the necessary paperwork on Tuesday, before announcing his candidacy on Tucker Carlson's show Fox News program. Carlson has advocated for McCloskey since the incident, which resulted in charges filed against the lawyer, which were eventually dropped after the DA on the case was blocked from pursuing it.

During the interview, McCloskey was quick to point out that he's "always been a Republican, but ... never been a politician." He lamented the fact that when it comes to making a real change in politics, "all we hear is talk; nothing ever changes." McCloskey urged free-thinking Americans to get into politics at every level so they can "pull the power back to the people."