WATCH: Bernie Sanders says Republicans are ‘laughing all the way to Election Day’

"What has bothered me very much is the Republicans are laughing all the way to Election Day. They have not had to cast one bloody vote ... which shows us where they're at. And we have got to change that," the democratic socialist from Vermont said on CNN's "State of the Union" over the weekend.

"What's most important is that the ideas we are fighting for are enormously popular. 70 to 80 percent of the American people want Medicare to negotiate prescription drug costs. People want to expand Medicare. People want to deal with the crisis of climate," Sanders claimed in the on-air segment.

"So, what we're talking about is what the American people want. And I think when you bring bills on the floor — we have allowed the Republicans to get away with murder. They haven't had to vote on anything," Sanders continued.

"Now, if they want to vote against lowering the cost of prescription drugs, expanding Medicaid, dealing with child care, dealing with housing, let them vote, and let Manchin and Sinema decide which side they are on," Sanders said.

President Joe Biden's agenda suffered a massive blow Wednesday after a bipartisan majority of senators shut down Democrat-led efforts to change the Senate filibuster, in order to pass "voting rights" bills.

Sens. Joe Manchin (D-WV) and Kyrsten Sinema (D-AZ) opposed key Democrat legislation despite weeks of negotiations between the White House and congressional lawmakers. Sinema has since been censured by Arizona Democrats.

"And when all of that shakes out, we'll see where we are. I have the feeling that we will be able to get 50 votes or more on some of these issues," Sanders stated.

"We could put that piece together and then pass something that's very significant."